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12
Apr

Scientist II – Tumor Immunology

Allen Institute for Immunology
Seattle, WA

The recently-launched Allen Institute for Immunology is seeking an outstanding individual to lead research efforts in the area of tumor immunology, including approaches to evaluate the effects of conventional and immuno-oncology therapies on cancer patient outcomes with an overarching goal of establishing new opportunities for future translational research at the mechanistic level.

The successful candidate will have a strong background in cellular immunological research, preferably human immunology, with a track record of both individual and team contributions in solving complex research problems. Strongest consideration will be given to candidates with a scientific background in tissue microenvironments, human tumor immunology and/or vaccine response tracking. Familiarity with contemporary approaches to deconstruct immunological pathways and translate hypotheses forward experimentally would be highly desired. Relevant experiences would also include familiarity with high-content flow cytometry, CYTOF, single cell transcriptomics, epigenetics and multiplexed imaging. Specific experiences in myeloid cell biology, hematopoiesis, TCR or BCR repertoire analyses and big data visualization are considered a plus.

Reporting to the Director of Experimental Immunology at the Allen Institute, the ideal candidate is a self-motivated team player who is willing to push the boundaries of human immunological research through scientific leadership, individual and team contributions and continuing scholarship on the ever-changing immunological landscape. The successful candidate will also have an established external network in immunology and excellent communication skills that can represent our efforts to our stakeholders internally and in external forum.

The Allen Institute offers exceptional working conditions, and nurtures diversity and team-science in an intellectually rich and stimulating setting. We provide a highly collaborative research environment offering the opportunity to interface closely with our molecular biologists, bioinformaticians, and partner institutions. Together we will illuminate key mechanistic pathways of the human immune system across autoimmune disease and cancer. For further details around the Institute’s research plans and partners: https://alleninstitute.org/what-we-do/immunology/.

Required Qualifications

  • PhD and/or MD with 4+ years post-doctoral research experience in immunology, cancer biology or related disciplines in either an academic or drug development setting
  • Strong record of cutting-edge research as evidenced by impactful publications
  • Experience in isolation and immunophenotyping immune populations for high dimensional analyses (15+ color flow cytometry, mass-cytometry or tissue imaging)
  • Working knowledge of the effects of tissue microenvironments on cellular phenotyping
  • Demonstrated ability to track and meet goals and milestones across multiple projects
  • Exceptional oral and written communication skills

Preferred Qualifications

  • Direct experience in human tumor immunology/immuno-oncology
  • Proven ability to drive meaningful data visualization form large data sets and work synergistically with bioinformaticians/systems biology teams
  • Able to work independently as well as in a collaborative high paced environment
  • Background in human myeloid cell populations and/or TCR/BCR repertoire analyses
  • Experience working with outside collaborators to achieve defined objectives

It is the policy of the Allen Institute to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, the Allen Institute will provide reasonable accommodations for qualified individuals with disabilities.

For more information, contact Jeannelle Roth at jeanneller@alleninstitute.org.